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Primary amoebic meningoencephalitis (PAM), a deadly disease caused by the ‘brain-eating amoeba’ Naegleria fowleri, is becoming more common in some areas of the world, and it has no effective treatment. Now, researchers have found that a compound isolated from the leaves of a traditional medicinal plant, Inula viscosa or ‘false yellowhead,’ kills the amoebae by causing them to commit cell suicide in lab studies, which could lead to new treatments.